Opioids Largely Ineffective in Lower Back Pain

People with chronic low back pain might get "modest, short-term pain relief" from opioids. But when it comes to long-term treatment, evidence to support the effectiveness of opioids is "lacking." That's the conclusion of an analysis by JAMA Internal Medicine ("Efficacy, Tolerability, and Dose-Dependent Effects of Opioid Analgesics for Low Back Pain" - May 23, 2016), after reviewing the results of 20 trials that included nearly 8,000 participants. As The New York Times reported ("Opioids Often Ineffective for Low Back Pain" – May 25, 2016), opioids "relieved pain slightly, but the effects were not clinically significant, and the medicines did little to improve disability. There was some evide

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